Top-and-bottom（T&B）blood bags have an outlet at the top and at the bottom of thecollecting bag, allowing simultaneous expression of plasma and red cells, whereasthe buffy coat remains in the collecting bag. The composition of bloodcomponents was investigated following manual separation of whole blood in aconventional 4-bag system (A) or automated separation in a ‘top-and-bottom’system (B).

To overcomeinter-donor differences, two units of whole blood were pooled and redistributedinto the original bags (A and B) prior to centrifugation. Leukocyte-poorplatelet concentrates (LPPC) were manufactured from both types of buffy coat (Aand B). The volumes of plasma, red cell concentrates (RCC) and buffy coat weresimilar in both methods. However, the residual leukocytes and platelets in theRCC from the top-and-bottom system were significantly lower than in theconventional system, 140 ± 59 times 10 6 (mean ± SD) versus 762 ± 228 times 106 , respectively (p<0.01). Both types of LPPC contained less than 10 7leukocytes and could be stored for 7 days maintaining a pH above 6.5. Weconclude that the top-and-bottom system enables automated and standardizedpreparation of RCC and plasma with a significantly better buffy-coat removalthan with manual processing.

 •  Sterile, pyrogen free, non toxic , ensure external sterility of the bags,

•  Slit present at the bottom of the bag  is satisfactory to hang the blood bag during transfusion. 

•  The plastic blood bag has a shelf life of minimum 2 years.    

•  Packing of goods: Individual blood bags are packed in a plastic pack and a maximum of 5 bags is packed in aluminum foil pack. These foil packs are packed in the corrugated boxes which indicates clearly and legibly the manufacture name,product name, batch number, quantity, manufacturing and expiry date, gross and net weight and consignee’s name address.     

•  Collection of blood volume can be 250ml, 350ml, 450ml, 500ml.  

DESIGN of Laishi Top  and bottom quadruple blood transfusion system  

•  No risk of contamination and airembolism closed system ] with all leak proof seals.  

•  Slit on both sides of the bags are enough to accommodate 5-10 ml volume test tubes. 

•  The capacity of the bag is enough to prevent any rupture of the bag from the seam when it is filled to the requisite volume of blood.      

TUBING  of Laishi Top  and bottom quadruple blood transfusion system    

•  Flexible and non kinking    

•  Non sticking     

•  Transparent      

•  Leak proof

•  Tubing has same ID/segment number as that on the bag       

•  The tubes has multiple printed ID/segment numbers  

NEEDLE  of Laishi Top  and bottom quadruple blood transfusion system  

•  16 gauge short bevel angled    

•  Siliconized for maximum donor comfort   

•  Rust proof        

•  Tightly fixed with hub covered with sterile guard   

•  Hermetically Sealed 

 EXTERNAL PORT  

•  Tamper proof and shouldn’t be recapped

•  Easily accessible      

PACKAGING   

•  Protective dual packaging [individual and aluminum] eliminating microbial contamination on surface maintaining thecontents of the bag.  

•  Easy to handle. 

ANTICOAGULANT of Laishi Top  and bottom quadruple blood transfusion system    

Each 100 ml CPD (U.S.P) contains:       

 - Citric Acid (anhydrous)………………………………………….. 0.299g

 - Sodium Citrate (dehydrate)……………………………..……… 2.63g

 - Monobasic Sodium Phosphate (monohydrate)……............... 0.222g

 - Dextrose (monohydrate)………………………………...………. 2.55g

 - Adenine…………………………………………………….....…… 0.0275g

Ifwith SAG-M, Each 100 ml SAG-M (U.S.P) contains:         

 -  Dextrose (monohydrate) ……………………………………..... 0.900 g

 - Sodium chloride…………………………………………....…….. 0.877 g

 - Adenine………………………………………………………..….. 0.0169 g

 - Mannitol…………………………………………………….....….. 0.525 g

 -  Waterfor injection   q.s……………………………………...….. 100ml

•  Clear And colorless   

•  No discoloration on storage at room temperature 

•  Manufacturer to provide anticoagulant quality check certificate.  

LABEL  of Laishi Top  and bottom quadruple blood transfusion system  

•  Non peel off     

•  Heat sealed labels   

•  Remain attached between room temperature to80 c with a transparent adhesive     

•  Label has printed manufacturing and expiry date and lot number of the bag      

•  Expiry date  2 years from the date of sterilization

•  Label provides sections for recording donor number, collection and expiration date of blood, blood group and Rh factor,Serology test results and signature of attendant.        

RESISTANCE TO DISTORTION      

•  When filled to normal capacity the bag is able to  with stand accelerate of 500g  for 30 mins at temperature 40 to 24 ℃ without becoming permanently distorted or rupture.   

•   bags are able to with stand temperature up – 80℃ without breakage.  

The blood bag manufacturing site has been engaged in the manufacturing since 1986, it has about 260 well trained workers and a strong professional technical and quality team. With modern and strict management, Laishi has became a reliable brand supplier for transfusion system in world transfusion industry. All the quadruple blood bags have passed strict TUV & GMP authentication system . 

Tag: Blood bag, quadurple blood bag, top and bottom quadruple blood bag, blood transfusion system, CPD blood bag, sag-m blood bag